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IMTEC-U1-snRNP-Antibodies

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IMTEC-U1-snRNP-Antibodies.pdf (91.02 KB)
  • IMTEC-U1-snRNP-Antibodies is an indirect solid-phase enzyme immunoassay (ELISA) for the qualitative and/or quantitative measurement of IgG class autoantibodies against U1-snRNP in human serum. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of mixed connective tissue disease.

  • Anti-U1-snRNP antibodies are considered to be a diagnostic marker of mixed connective tissue disease (MCTD), which is also referred to as ''Sharp's syndrome”. Used in this indication, the antibodies achieve a sensitivity of 100% (per definition) and a specificity of 98% in the absence of both anti-Sm and anti-dsDNA antibodies.

  • Code ITC70022  96Tests

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