IMTEC-GBM-Antibodies is an indirect solid-phase enzyme immunoassay (ELISA) for the quantitative measurement of IgG class autoantibodies against glomerular basement membrane antigen (GBM, collagen IV) in human serum. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of rapid progressive glomerulonephritis (RPGN) and Goodpasture syndrome.

Anti-GBM antibodies (anti-Glomerular Basement Membrane antibodies) can be detected in about 90% of patients with Goodpasture's syndrome. While Goodpasture's syndrome is a relatively rare condition (0.5% of all patients with renal diseases), it is rapidly progressive and, if not treated, fatal in of 75-90%. An early diagnosis and an immediate and correct treatment decreases the lethality dramatically

Code ITC82070  96Tests