IMTEC-MPO-ANCA is an indirect solid-phase enzyme immunoassay (ELISA) for the quantitative measurement of IgG class autoantibodies against myeloperoxidase in human serum. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of autoimmune vasculitides such as microscopic polyangiitis and Churg-Strauss syndrome.

Proteinase 3 (PR3) is the main target of cytoplasmic anti-neutrophil cytoplasm antibodies (cANCA). In contrast to that, perinuclear ANCA (pANCA) mainly react with myeloperoxidase (MPO).

Code ITC82030  96Tests