IMTEC-Nucleosome-Antibodies is an enzyme immunoassay (ELISA) for the quantitative measurement of IgG class autoantibodies against nucleosomes in human serum. The assay is intended for in vitro diagnostic use only as an aid in the diagnosis of systemic lupus erythematosus.

Anti-Nucleosome antibodies are regarded as a diagnostic marker for systemic lupus erythematosus (SLE). The antibodies can be detected in almost 100% of all patients with active SLE and in 62% of those with inactive SLE (the corresponding frequency for the detection of dsDNA antibodies in SLE is only 3.3 %). They are regarded as an early marker of the exacerbation of SLE, since they occur sooner than dsDNA antibodies.

Code ITC59002  96Tests